Boniva (Ibandronate)




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BONIVA (Ibandronate) is a prescription medication prescribed to treat and prevent postmenopausal osteoporosis.

BONIVA works by binding to hydroxyapatite, a mineral that is part of the bone matrix. By binding to the bone, BONIVA prevents the normal breakdown of bone by inhibiting bone turnover. It also directly strengthens bone by incorporating it into the matrix.


The normal BONIVA dosage is to take a 150 mg tablet by mouth once monthly (every 28 days).

Take BONIVA on an empty stomach with 6-8 oz of water. Take the tablet 60 minutes before the first food, drink, or medication of the day. Do not lie down for 60 minutes after taking BONIVA.

Your doctor may have you take calcium and vitamin D supplements while taking BONIVA.

BONIVA should be taken for 3-5 years. It should usually be discontinued after 5 years of use.


The active ingredient in BONIVA is Ibandronate sodium, which is also the name of the BONIVA generic.


Speak with your doctor if you have gastrointestinal issues before you start taking BONIVA, as it can cause irritation that makes these issues worse. Examples of gastrointestinal issues include Barrett’s esophagus, duodenitis, dysphagia, esophageal diseases, gastritis, and ulcers.

BONIVA can lower calcium, so your calcium levels should be monitored while taking it.

Tell your doctor if severe bone, joint, muscle, or jaw pain occur while taking BONIVA. You may need to stop taking BONIVA and switch to another medication.

Side Effects

Common adverse reactions that occur while taking BONIVA include:

  • Asthenia
  • Back pain
  • Bronchitis
  • Diarrhea
  • Dyspepsia
  • Headache
  • Myalgia
  • Pain in extremity
  • Pneumonia
  • Tooth disorder

Speak to your doctor or pharmacist for a full list of BONIVA side effects.

Buy BONIVA and BONIVA generic from an online retailer like Canada Pharmacy.


  1. Boniva [package insert]. San Fransisco, CA: Genentech; 2015.
  2. Medical News Today, What to know about indigestion or dyspepsia, Retrivied April 2020 
  3. WebMD, A Visual Guide to Osteoporosis, Retrivied April 2020