Combigan(Brimonidine / Timolol)




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Product Details


Glaucoma Treatment

Combigan (Brimonidine/Timolol)

Combigan is a combination of 2 drugs used to treat high-pressure symptoms of the eye, namely glaucoma (open-angle type) and some other eye diseases like ocular hypertension. Lowering the pressure in the eye helps prevent blindness in these conditions. Combigan eye drops are used when single-ingredient drugs are unable to treat glaucoma.

The 2 drugs in Cambigan are brimonidine and timolol. Brimonidine is an alpha agonist. It acts by decreasing the amount of fluid formed in the eye along with improving the fluid drainage from within the eye. Timolol belongs to the group of beta blockers. It decreases the amount of fluid formed within the eye. The effect of both drugs results in lowering the intra ocular pressure and giving relief to the patient.

Combigan eye drops are not recommended for children under 2 years of age due to increased risk of side effects.

You can buy Combigan eye drops for glaucoma treatment from Canada Pharmacy and have it delivered to you.


Before using Combigan eye drops, read the patient’s leaflet provided by the pharmacist. The usual dose is 1 drop in the eye pouch every 12 hours or as directed by your physician. To administer the eye drop, with clean washed hands, tilt your head back. Pull down the lower eyelid and squeeze out a drop in the lower pouch. Close your eyes for 2-3 minutes, looking down, without blinking or squinting. Gently press on the inner angle of the eye to distribute the drug evenly. Repeat with the other eye.


Active ingredients are:

  • Brimonidine 0.2%
  • Timolol 0.5%


Before starting treatment with Combigan, if following conditions are present, consult your doctor.

  • Asthma or COPD
  • Serious heart problem like AV block
  • Congestive heart failure
  • Coronary artery disease
  • Stroke or blood clot
  • High or low blood pressure
  • Depression
  • Diabetes
  • Any allergies
  • Thyroid disorder
  • History of glaucoma

Side Effects

Following side effects can be associated with Combigan and may require the consultation of the doctor.

  • Slow or uneven heart rate
  • Palpitations
  • Shallow breathing, faintness
  • Severe swelling, redness or discomfort in or around the eye
  • Eye pain
  • Increased watering of the eye
  • Numbness or tingling in the hands or feet
  • Drowsiness, tiredness
  • Mild stinging or burning in eyes
  • Allergic reaction