Entresto Medication Indications
ENTRESTO is a prescription medicine used to reduce the risk of death and hospitalization in people with certain types of long-lasting (chronic) heart failure. ENTRESTO is usually used with other heart failure therapies, in place of an ACE inhibitor or other ARB therapy.
The recommended starting dose of Entresto is one tablet of 49 mg/51 mg twice daily, except in certain situations. The dose should be doubled at 2-4 weeks to the target dose of one tablet of 97 mg/103 mg twice daily, as tolerated by the patient. Entresto may be administered with or without food. The tablets must be swallowed with a glass of water.
Each film-coated tablet contains sacubitril and valsartan (as sacubitril valsartan sodium salt complex) as active ingredients.
Do not take ENTRESTO if you: 1)are allergic to sacubitril or valsartan or any of the ingredients in ENTRESTO 2)have had an allergic reaction including swelling of your face, lips, tongue, throat (angioedema) or trouble breathing while taking a type of medicine called an angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB) 3)take an ACE inhibitor medicine. Do not take ENTRESTO for at least 36 hours before or after you take an ACE inhibitor medicine. Talk with your doctor or pharmacist before taking ENTRESTO if you are not sure if you take an ACE inhibitor medicine have diabetes and take a medicine that contains aliskiren
ENTRESTO may cause serious side effects including: angioedema that may cause trouble breathing and death. Get emergency medical help right away if you have symptoms of angioedema or trouble breathing. Do not take ENTRESTO again if you have had angioedema while taking ENTRESTO. People who are Black or who have had angioedema and take ENTRESTO may have a higher risk of having angioedema low blood pressure (hypotension). Call your doctor if you become dizzy or lightheaded, or you develop extreme fatigue kidney problems increased amount of potassium in your blood The most common side effects were low blood pressure, high potassium, cough, dizziness, and kidney problems.