Generic Equivalent – Anusol HC Ointment (Hydrocortisone / Zinc Sulfate)




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Anusol HC Ointment Utilization and Effects

Anusol HC Ointment

Anusol HC Ointment is prescribed to treat minor pain, swelling, itching, or any discomfort caused by hemorrhoids and other issues of the anal area. Hydrocortisone is a corticosteroid that reduces redness, itching, and swelling.

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Before use, clean the affected area with mild soap and water, rinse well, and pat dry. To apply this product inside the anus, use the applicator tip/cap/nozzle, following all instructions in the product package, or use as directed by your doctor.

Fill the applicator with medication from the container as directed. Gently insert the applicator tip just 1/2 to 1 inch inside the anus and apply in and around the anal opening as directed.

Do not insert your finger or any part of the container into the anus, and do not insert the applicator tip/nozzle more than 1/2 to 1 inch inside the anus. If you are using a single-use tube and applicator, discard after one use.

To apply the product to the outside of the anus only, use your finger to apply a small amount of cream or ointment to the affected area and rub in gently.


Each tube contains zinc sulfate monohydrate 0.5% and hydrocortisone acetate 0.5% in a petroleum ointment base.

Nonmedicinal ingredients include poloxyl-2-oleyl ether, calcium phosphate, mineral oil, methylparaben, petrolatum, and propylparaben.


Do not cover the area with plastic or waterproof bandages unless directed to do so by your doctor. Covering the treated area may increase the absorption of the medication through the skin. This may improve how well the drug works, but it may also increase the risk of side effects.

Side Effects

Redness, burning, or itching may occur at the place where you have applied the ointment. If any of these effects worsen or continues, consult your doctor immediately.

Tell your doctor right away if any of these unlikely but serious side effects occur, i.e., rectal bleeding, change in skin appearance, skin redness/tenderness/pus or other signs of infection.

A very serious allergic reaction to this drug is unusual. However, seek immediate medical help if you suffer from any serious allergic reaction.