Janumet XR (Sitagliptin / Metformin)


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Janumet XR (Sitagliptin / Metformin)


Janumet XR Use and Indications

Janumet XR (Sitagliptin/Metformin)

Janumet XR is used to control high blood sugar. This drug is used with a proper diet and exercise plan and mostly by patients with type 2 diabetes.

Janumet XR contains sitagliptin and metformin. Sitagliptin works by increasing the substance called incretins that is naturally present in our body.  Incretins help in controlling the level of blood sugar by increasing the release of insulin right after a meal.

Incretins also help to decrease the amount of sugar made by the liver. Metformin helps in restoring the body’s proper response to the insulin you produce naturally. It also decreases the amount of sugar made in the liver and absorbed in the stomach and intestines.

Controlling the high blood sugar level prevents the kidney from being damaged, nerve problems, blindness and sexual function problems. You can buy the medicine Janumet XR from Canada Pharmacy.


Janumet XR should be taken orally and can be consumed daily with a meal preferably in the evening. Make sure that you do not crush or chew these extended-release tablets; doing this can release the entire drug at once increasing the side effects of Janumet XR.

Make sure that you drink a lot of water and plenty of fluids with this medication unless advised by your doctor otherwise.

The dosage of Janumet XR depends on the severity of your medical condition and how you respond to the treatment.


Janumet XR ingredients include:

  • Povidone,
  • Hypromellose
  • Colloidal silicon dioxide
  • Sodium stearyl fumarate
  • Propyl gallate
  • Polyethylene glycol
  • Kaolin


  • Let your physician know about the medical treatments and medicines you are using.
  • This medication might increase your blood pressure so check your blood pressure regularly.
  • Let your doctor know if you have any allergies before using it.
  • Before using this medicine, let your doctor know if you are allergic to Sitagliptin Metformin.

Too much metformin can build up in the body and lead to a serious condition called lactic acidosis. If you experience symptoms of lactic acidosis such as tiredness, dizziness, blue or cold skin, slow and irregular heartbeat, then get medical help right away.

Side Effects

Some common side effects of this drug are:

  • Nausea
  • Vomiting
  • Upset stomach
  • Diarrhea
  • Headache
  • Metallic taste in the mouth

Some serious but rare side effects of this drug include:

  • Join pain
  • Change in the amount of urine
  • Unusual skin blisters
  • Shortness of breath
  • Swelling of ankles and feet
  • Unusual tiredness
  • Sudden weight gain


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.